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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Abstract:

Migraine is a debilitating neurological disorder affecting around one in seven people worldwide, but its molecular mechanisms remain poorly understood. There is some debate about whether migraine is a disease of vascular dysfunction or a result of neuronal dysfunction with secondary vascular changes. Genome-wide association (GWA) studies have thus far identified 13 independent loci associated with migraine. To identify new susceptibility loci, we carried out a genetic study of migraine on 59,...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/ng.3598

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Role:
Author
ORCID:
0000-0002-0073-4675
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Role:
Author
ORCID:
0000-0003-1982-6569
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Genetics Journal website
Volume:
48
Issue:
8
Pages:
856-866
Place of publication:
United States
Publication date:
2016-06-20
Acceptance date:
2016-05-26
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Pmid:
27322543
Pubs id:
630932
Local pid:
pubs:630932
Language:
English
Keywords:
Subjects:
Format:
Print-Electronic

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