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The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis

Abstract:

Radical cure of Plasmodium vivax malaria in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals employs weekly primaquine dosing. This is the only recommended regimen for this patient sub-group. If national malaria programs mandate daily primaquine dosing (the recommended regimen for G6PD normal individuals), then G6PD testing before prescription is necessary to avoid iatrogenic haemolysis in G6PD deficient individuals. In this case series, two P. vivax infected patients with unkno...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.12688/wellcomeopenres.15100.2

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Tropical Medicine
ORCID:
0000-0003-4550-0431
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ORCID:
0000-0002-2758-0872
Gornsawun, G More by this author
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Publisher:
F1000 Research Publisher's website
Journal:
Wellcome Open Research Journal website
Publication date:
2019-04-09
Acceptance date:
2019-02-06
DOI:
ISSN:
2398-502X
Pubs id:
pubs:991131
URN:
uri:a5bd0910-13cd-4bd6-b967-4c9a0f6a74d4
UUID:
uuid:a5bd0910-13cd-4bd6-b967-4c9a0f6a74d4
Local pid:
pubs:991131
Keywords:

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