Journal article
Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells.
- Abstract:
-
Permeabilized patch whole-cell voltage clamp methods were used to investigate the effects of isoprenaline (ISO) on total delayed rectifier potassium current, iK, in rabbit sino-atrial (SA) node pacemaker cells; total iK is composed of the rapidly activating iKr and the slowly activating iKs, but predominantly iKr in this species. ISO (20 nM) increased the amplitude of total iK and caused a negative shift of approximately 10 mV in the activation curve for iK, both in the absence and in the pre...
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- Publication status:
- Published
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- Publisher copy:
- 10.1017/s0958067000019151
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Bibliographic Details
- Journal:
- Experimental physiology
- Volume:
- 85
- Issue:
- 1
- Pages:
- 27-35
- Publication date:
- 2000-01-01
- DOI:
- EISSN:
-
1469-445X
- ISSN:
-
0958-0670
- Source identifiers:
-
106427
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:106427
- UUID:
-
uuid:a5b4acaf-99ba-43e2-9535-ac2331300e53
- Local pid:
- pubs:106427
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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