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Journal article

Effect of beta-propiolactone--an inhibitor of HTLV III/LAV activity--on immunological analyses.

Abstract:

beta-Propiolactone (BPL) inactivates LAV/HTLV III, the retrovirus associated with acquired immune deficiency syndrome (AIDS). Addition to specimens from patients with suspected AIDS or antibodies to LAV/HTLV III could reduce any occupational risk to laboratory staff. This study demonstrates that BPL treatment does not significantly affect the immunological analyses commonly required on these patients, namely measurements of serum immunoglobulins, complement components C3 and C4 and other seru...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Journal of immunological methods
Volume:
95
Issue:
1
Pages:
113-116
Publication date:
1986-12-05
DOI:
EISSN:
1872-7905
ISSN:
0022-1759
URN:
uuid:a5a10c0d-73d1-4651-8d92-ff776db9aac6
Source identifiers:
66927
Local pid:
pubs:66927

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