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Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.

Abstract:

The feasibility of a malaria vaccine is supported by the fact that children in endemic areas develop naturally acquired immunity to disease. Development of disease immunity is characterized by a decrease in the frequency and severity of disease episodes over several years despite almost continuous infection, suggesting that immunity may develop through the acquisition of a repertoire of specific, protective antibodies directed against polymorphic target antigens. Plasmodium falciparum erythro...

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Publication status:
Published

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Publisher copy:
10.1038/nm0398-358

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
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Journal:
Nature medicine
Volume:
4
Issue:
3
Pages:
358-360
Publication date:
1998-03-05
DOI:
EISSN:
1546-170X
ISSN:
1078-8956
URN:
uuid:a576ea0f-0ec5-4752-a84a-9189f5647f09
Source identifiers:
3805
Local pid:
pubs:3805

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