Journal article
Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?
- Abstract:
-
The Holliday junction (HJ) is a central intermediate of homologous recombination. Its cleavage is critical for the formation of crossover recombinants during meiosis, which in turn helps to establish chiasmata and promote genetic diversity. Enzymes that cleave HJs, called HJ resolvases, have been identified in all domains of life except eukaryotic nuclei. Controversially, the Mus81-Eme1 endonuclease has been proposed to be an example of a eukaryotic nuclear resolvase. However, hitherto little...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/sj.emboj.7601645
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Bibliographic Details
- Journal:
- EMBO journal
- Volume:
- 26
- Issue:
- 7
- Pages:
- 1891-1901
- Publication date:
- 2007-04-01
- DOI:
- EISSN:
-
1460-2075
- ISSN:
-
0261-4189
- Source identifiers:
-
11314
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:11314
- UUID:
-
uuid:a56a238a-eb9e-4160-9cf4-b33cb5e6f64d
- Local pid:
- pubs:11314
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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