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Global gene expression responses of fission yeast to ionizing radiation.

Abstract:

A coordinated transcriptional response to DNA-damaging agents is required to maintain genome stability. We have examined the global gene expression responses of the fission yeast Schizosaccharomyces pombe to ionizing radiation (IR) by using DNA microarrays. We identified approximately 200 genes whose transcript levels were significantly altered at least twofold in response to 500 Gy of gamma IR in a temporally defined manner. The majority of induced genes were core environmental stress respon...

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Publication status:
Published

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Publisher copy:
10.1091/mbc.e03-08-0569

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
Molecular biology of the cell
Volume:
15
Issue:
2
Pages:
851-860
Publication date:
2004-02-05
DOI:
EISSN:
1939-4586
ISSN:
1059-1524
URN:
uuid:a55b07b5-dd1e-43f5-b8e1-9e1a7e7b782a
Source identifiers:
315395
Local pid:
pubs:315395

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