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A comparison of artesunate alone with combined artesunate and quinine in the parenteral treatment of acute falciparum malaria.

Abstract:

In some areas clinicians have combined parenteral artesunate and quinine in the belief that the 2 drugs would be additive or synergistic in severe malaria. A randomized comparison of the effectiveness of intravenous (i.v.) artesunate versus i.v. artesunate and i.v. quinine together on parasite clearance was conducted in 1998/99 amongst 69 patients with uncomplicated and severe Plasmodium falciparum malaria in western Thailand. The parasite clearance time did not differ significantly between t...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Chierakul, W More by this author
Ruangveerayuth, R More by this author
Silamut, K More by this author
Teerapong, P More by this author
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Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
95
Issue:
5
Pages:
519-523
Publication date:
2001
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:a537f42a-8edf-4a84-8cb1-cadf1d2d4adb
Source identifiers:
11871
Local pid:
pubs:11871

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