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Journal article

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

Abstract:

OBJECTIVES: To determine whether CD8 T lymphocytes from HIV-1-infected patients expressing B*5701 and B*5703 show broad cross-reactivity against different variants of a conserved p24 epitope, which might account for the good prognosis of HIV-1-infected individuals with HLA-B*57. DESIGN: B*5701+ and B*5703+ were recruited from Nairobi, Kenya and from Oxford, UK. All patients had been HIV positive for at least 8 years and could be categorized as slow progressors. METHODS: CD8 cytotoxic T cell ...

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Publication status:
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Rostron, T More by this author
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Journal:
AIDS (London, England)
Volume:
16
Issue:
7
Pages:
961-972
Publication date:
2002-05-05
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
URN:
uuid:a506456e-84b4-496a-97fd-faa06be99d7d
Source identifiers:
9264
Local pid:
pubs:9264

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