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Journal article

T cell selection during the evolution of CD8+ T cell memory in vivo.

Abstract:

Memory T cell responses are frequently highly restricted in terms of receptor usage. How and when such clonotypic dominance is established remains poorly understood. Here we have investigated the evolution of the T cell responses to an epitope from Epstein-Barr virus (EBV), (FLRGRAYGL), by analyzing TCR use of clones specific for this epitope, derived from peripheral blood mononuclear cells taken from individuals early during primary EBV infection and up to 3 years later. We show that, in a g...

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Publication status:
Published

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Journal:
European journal of immunology
Volume:
28
Issue:
12
Pages:
4382-4390
Publication date:
1998-12-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:a4fc2b39-ec3e-4d32-b8a7-9a2caad746bf
Source identifiers:
36274
Local pid:
pubs:36274

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