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Journal article

Whole-exome sequencing studies of nonhereditary (sporadic) parathyroid adenomas.

Abstract:

CONTEXT: Genetic abnormalities, such as those of multiple endocrine neoplasia type 1 (MEN1) and Cyclin D1 (CCND1) genes, occur in <50% of nonhereditary (sporadic) parathyroid adenomas. OBJECTIVE: To identify genetic abnormalities in nonhereditary parathyroid adenomas by whole-exome sequence analysis. DESIGN: Whole-exome sequence analysis was performed on parathyroid adenomas and leukocyte DNA samples from 16 postmenopausal women without a family history of parathyroid tumors or MEN1 and in...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1210/jc.2012-2303

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
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Medical Research Council More from this funder
National Institute for Health Research Oxford Biomedical Research Centre More from this funder
Wellcome Trust More from this funder
Publisher:
Endocrine Society Publisher's website
Journal:
The Journal of clinical endocrinology and metabolism Journal website
Volume:
97
Issue:
10
Pages:
E1995-E2005
Publication date:
2012-10-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:a4ddaded-52e0-4b49-a6a6-76d71db6720d
Source identifiers:
344135
Local pid:
pubs:344135

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