Journal article icon

Journal article

Combinatorial effects of malaria season, iron deficiency, and inflammation determine plasma hepcidin concentration in African children.

Abstract:

Hepcidin is the master regulatory hormone that governs iron homeostasis and has a role in innate immunity. Although hepcidin has been studied extensively in model systems, there is less information on hepcidin regulation in global health contexts where iron deficiency (ID), anemia, and high infectious burdens (including malaria) all coexist but fluctuate over time. We evaluated iron status, hepcidin levels, and determinants of hepcidin in 2 populations of rural children aged ≤8 years, in the ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Atkinson, SH More by this author
Armitage, AE More by this author
Khandwala, S More by this author
Mwangi, TW More by this author
Expand authors...
Publisher:
American Society of Hematology
Journal:
Blood
Volume:
123
Issue:
21
Pages:
3221-3229
Publication date:
2014-05-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:a4d2ef0c-23dc-4b81-a77d-7eaaf70ab37e
Source identifiers:
451025
Local pid:
pubs:451025

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP