Journal article
Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis
- Abstract:
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BACKGROUND: C/EBPa and C/EBPb are transcription factors with tissue specific expression regulating several important cellular processes. They work by recruiting protein complexes to a common DNA recognition motif and both are able to compensate each other's absence in many cell types, thus showing functional redundancy. They also play distinct roles in specific cellular pathways and their abnormal functioning gives raise to different human pathologies. METHODS: To investigate the molecular ba...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 1.6MB)
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- Publisher copy:
- 10.1016/j.bbagen.2016.10.002
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Authors
Funding
European Molecular Biology Laboratory
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Biochimica et Biophysica Acta (BBA) - General Subjects Journal website
- Volume:
- 1861
- Issue:
- 2
- Pages:
- 467–476
- Publication date:
- 2016-10-13
- Acceptance date:
- 2016-10-04
- DOI:
- ISSN:
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0304-4165
- Source identifiers:
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653454
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:653454
- UUID:
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uuid:a47d5715-0984-49e4-907a-ae15f78914a6
- Local pid:
- pubs:653454
- Deposit date:
- 2016-11-01
Terms of use
- Copyright holder:
- Elsevier BV
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Elsevier B.V. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.bbagen.2016.10.002
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