- Abstract:
-
The maintenance of a relatively low intracellular Na+:K+ ratio is essential for the functioning of a wide range of cellular processes, and is achieved principally by the activity of the membrane-bound Na+, K(+)-ATPase. Chondrocytes, the cells of articular cartilage, exist in an ionic environment where the free extracellular [Na+] is higher (250-400 mM) than that of most other tissues (approximately 140 mM) owing to the fixed negative charges on glycosaminoglycans in the extracellular matrix. ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s1357-2725(96)00150-1
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- Journal:
- The international journal of biochemistry and cell biology
- Volume:
- 29
- Issue:
- 4
- Pages:
- 649-657
- Publication date:
- 1997-04-05
- DOI:
- EISSN:
-
1878-5875
- ISSN:
-
1357-2725
- URN:
-
uuid:a452693d-f30e-4e4b-bcdd-8b2e77a43116
- Source identifiers:
-
433366
- Local pid:
- pubs:433366
- Copyright date:
- 1997
Journal article
Immunologic and autoradiographic localisation of the Na+, K(+)-ATPase in articular cartilage: upregulation in response to changes in extracellular Na+ concentration.
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