Journal article icon

Journal article

In vivo characteristics of human immunodeficiency virus type 1 intersubtype recombination: Determination of hot spots and correlation with sequence similarity

Abstract:

Recombination plays a pivotal role in the evolutionary process of many different virus species, including retroviruses. Analysis of all human immunodeficiency virus type 1 (HIV-1) intersubtype recombinants revealed that they are more complex than described initially. Recombination frequency is higher within certain genomic regions, such as partial reverse transcriptase (RT), vif/vpr, the first exons of tat/rev, vpu and gp41. A direct correlation was observed between recombination frequency an...

Expand abstract

Actions


Access Document


Publisher copy:
10.1099/vir.0.19180-0

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Expand authors...
Journal:
Journal of General Virology
Volume:
84
Issue:
10
Pages:
2715-2722
Publication date:
2003-10-01
DOI:
ISSN:
0022-1317
URN:
uuid:a41a7c63-c16f-4ad8-96b1-1c75a8a39997
Source identifiers:
278943
Local pid:
pubs:278943
Language:
English

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP