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Thesis

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C

Abstract:

For both influenza viruses and hepatitis C viruses, T cell responses to conserved antigens are one strategy for the human host to control the spread of infection. Such T cell responses can be generated with the use of viral vectored vaccines.

Initially I show that the viral vectored vaccine MVA-NP+M1 can boost memory T cell responses to influenza A virus in adults aged over 50 years old. However within this group, MVA-NP+M1 had reduced immunogenicity in adults who were aged over 70 ...

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Institution:
University of Oxford
Research group:
Jenner Institute
Oxford college:
St Cross College
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)

Contributors

Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:a3efad5e-d619-4641-8c05-2d4e336a10dc
Local pid:
ora:10581

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