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Journal article

Serial brain MRI at 3-6 month intervals as a surrogate marker for Alzheimer's disease

Abstract:

A surrogate marker is needed for Alzheimer's disease (AD) both to aid diagnosis and to assess interventions. Despite widespread use, brain imaging markers have largely been confounded by overlap with "normal" ageing. 39 elderly subjects completed up to four serial volumetric brain MRI scans with intervals from 2.5 months to 7 months. By National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) criteria, five subjects had probable AD, two possible AD and 32 were negati...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1259/bjr.75.894.750506

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Publisher:
British Institute of Radiology Publisher's website
Journal:
The British journal of radiology Journal website
Volume:
75
Issue:
894
Pages:
506-513
Publication date:
2002-06-01
DOI:
EISSN:
1748-880X
ISSN:
0007-1285
Pubs id:
pubs:97433
URN:
uri:a3de5c55-457f-45e4-8045-ff2361dc6864
UUID:
uuid:a3de5c55-457f-45e4-8045-ff2361dc6864
Local pid:
pubs:97433
Language:
English
Keywords:

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