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Secretion of adipokines by human adipose tissue in vivo: Partitioning between capillary and lymphatic transport

Abstract:

Peptides secreted by adipose tissue (adipokines) may enter blood via capillaries or lymph. The relative importance of these pathways for a given adipokine might influence its biological effects. Because this has not been studied in any species, we measured the concentrations of seven adipokines and eight nonsecreted proteins in afferent peripheral lymph and venous plasma from 12 healthy men. Data for nonsecreted proteins were used to derive indices of microvascular permeability, which in conj...

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Publisher copy:
10.1152/ajpendo.00058.2011

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Journal:
American Journal of Physiology - Endocrinology and Metabolism
Volume:
301
Issue:
4
Publication date:
2011-10-05
DOI:
EISSN:
1522-1555
ISSN:
0193-1849
URN:
uuid:a3c679be-a294-4e08-80c4-8ed55b87d2cf
Source identifiers:
186408
Local pid:
pubs:186408

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