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Journal article

Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.

Abstract:

We have developed an automated, highly sensitive and specific method for identifying and enumerating circulating tumour cells (CTCs) in the blood. Blood samples from 10 prostate, 25 colorectal and 4 ovarian cancer patients were analysed. Eleven healthy donors and seven men with elevated serum prostate-specific antigen (PSA) levels but no evidence of malignancy served as controls. Spiking experiments with cancer cell lines were performed to estimate recovery yield. Isolation was performed eith...

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Publication status:
Published

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Publisher copy:
10.1038/sj.bjc.6604545

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
British journal of cancer
Volume:
99
Issue:
5
Pages:
789-795
Publication date:
2008-09-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:a3943c8b-1e15-4ee5-9f0e-455b1977435e
Source identifiers:
28248
Local pid:
pubs:28248

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