- Abstract:
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Objective To replicate and refine the reported association of ankylosing spondylitis (AS) with two non-synonymous single nucleotide polymorphisms (nsSNPs) on chromosome 16q22.1.
Methods Firstly, 730 independent UK patients with AS were genotyped for rs9939768 and rs6979 and allele frequencies were compared with 2879 previously typed historic disease controls. Secondly, the two data sets were combined in meta-analyses. Finally, 5 tagging SNPs, locate...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1136/ard.2009.115147
-
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- Publisher:
- BMJ Publishing Group Ltd Publisher's website
- Journal:
- Annals of the rheumatic diseases Journal website
- Volume:
- 69
- Issue:
- 6
- Pages:
- 1243-1246
- Publication date:
- 2010-06-05
- DOI:
- EISSN:
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1468-2060
- ISSN:
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0003-4967
- URN:
-
uuid:a380d76f-a4ec-4f4a-b7fb-73b173a44dcc
- Source identifiers:
-
108333
- Local pid:
- pubs:108333
- Copyright holder:
- BMJ Publishing Group Ltd
- Copyright date:
- 2010
- Notes:
- The full-text of this article is not currently available in ORA, but you may be able to access the article via the publisher copy link on this record page.
Journal article
The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD).
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National Institute for Health
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