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Journal article

Cutaneous, but not airway, latex exposure induces allergic lung inflammation and airway hyperreactivity in mice.

Abstract:

As respiratory symptoms are common in addition to skin reactions in natural rubber latex allergy, we investigated the significance of different allergen exposure routes in the development of lung inflammation and airway hyperreactivity (AHR). Both intracutaneous (IC) and intraperitoneal (IP) exposure followed by airway challenge with latex proteins induced an influx of mononuclear cells and eosinophils to the lungs. AHR and lung mucus production increased significantly after IC and IP but not...

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Journal:
The Journal of investigative dermatology
Volume:
125
Issue:
5
Pages:
962-968
Publication date:
2005-11-05
DOI:
EISSN:
1523-1747
ISSN:
0022-202X
URN:
uuid:a375b166-13d3-4265-8006-a4ff2902de68
Source identifiers:
387515
Local pid:
pubs:387515

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