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Close association of invading Plasmodium berghei and beta integrin in the Anopheles gambiae midgut.

Abstract:

We have used confocal microscopy and an antibody against Anopheles gambiae beta integrin to study this protein's distribution in the mosquito midgut and its relationship to invading Plasmodium berghei parasites. An extensive reorganization of integrin is seen to take place in the midgut epithelial cells following the uptake of either non-infected or parasite-infected blood meal, probably reflecting the reshaping of the gut due to the presence of the food bolus and the peritrophic membrane tha...

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Publisher copy:
10.1002/arch.20077

Authors


Mahairaki, V More by this author
Sidén-Kiamos, I More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Journal:
Archives of insect biochemistry and physiology
Volume:
60
Issue:
1
Pages:
13-19
Publication date:
2005-09-05
DOI:
EISSN:
1520-6327
ISSN:
0739-4462
URN:
uuid:a36b768a-d7f4-4d69-b7b6-c10942e5945e
Source identifiers:
271594
Local pid:
pubs:271594

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