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Journal article : Review

Blood pressure and the brain: the neurology of hypertension

Abstract:
Hypertension affects more than one in four adults. The brain is an early target of hypertension-induced organ damage, and may manifest as stroke, subclinical cerebrovascular abnormalities and dementia. Hypertension-related small vessel disease can cause vascular dementia and can potentiate Alzheimer's pathology, lowering the threshold at which signs and symptoms manifest. Many hypertensive emergencies may also have a neurological presentation, such as hypertensive encephalopathy, haemorrhagic stroke or pre-eclampsia. Here we highlight the importance of blood pressure in maintaining brain health and the brain's role in controlling blood pressure.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1136/practneurol-2019-002269

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Sub department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0002-4318-2030
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Sub department:
Clinical Neurosciences
Role:
Author


Publisher:
BMJ Publishing Group
Journal:
Practical Neurology More from this journal
Volume:
20
Issue:
2
Pages:
100-108
Publication date:
2019-09-26
Acceptance date:
2019-09-14
DOI:
EISSN:
1474-7766
ISSN:
1474-7758
Pmid:
31558584


Language:
English
Keywords:
Subtype:
Review
Pubs id:
1064022
Local pid:
pubs:1064022
Deposit date:
2020-02-20

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