Evidence of genetic association between TNFRSF1A encoding the p55 tumour necrosis factor receptor, and ankylosing spondylitis in UK Caucasians.

Karaderi, T; Pointon, JJ; Wordsworth, TW; Harvey, D; Appleton, LH; Cohen, CJ; Farrar, C; Harin, A; Brown, MA; Wordsworth, BP

Abstract:

OBJECTIVES: To replicate the possible genetic association between ankylosing spondylitis (AS) and TNFRSF1A. METHODS: TNFRSF1A was re-sequenced in 48 individuals with AS to identify novel polymorphisms. Nine single nucleotide polymorphisms (SNPs) in TNFRSF1A and 5 SNPs in the neighbouring gene SCNN1A were genotyped in 1604 UK Caucasian individuals with AS and 1019 matched controls. An extended study was implemented using additional genotype data on 8 of these SNPs from 1400 historical controls...

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APA Style

Karaderi, T., Pointon, J. J., Wordsworth, T. W., Harvey, D., Appleton, L. H., Cohen, C. J., Farrar, C., Harin, A., Brown, M. A., & Wordsworth, B. P. (2012). Evidence of genetic association between TNFRSF1A encoding the p55 tumour necrosis factor receptor, and ankylosing spondylitis in UK Caucasians. Clinical and Experimental Rheumatology, 30(1), 110–113.

MLA Style

Karaderi, T., et al. “Evidence of Genetic Association between TNFRSF1A Encoding the p55 Tumour Necrosis Factor Receptor, and Ankylosing Spondylitis in UK Caucasians.” Clinical and Experimental Rheumatology, vol. 30, no. 1, 2012, pp. 110–13.

Chicago Style

Karaderi, T, JJ Pointon, TW Wordsworth, D Harvey, LH Appleton, CJ Cohen, C Farrar, A Harin, MA Brown, and BP Wordsworth. 2012. “Evidence of Genetic Association between TNFRSF1A Encoding the p55 Tumour Necrosis Factor Receptor, and Ankylosing Spondylitis in UK Caucasians.” Clinical and Experimental Rheumatology 30 (1): 110–13.
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