Journal article icon

Journal article

Evidence of genetic association between TNFRSF1A encoding the p55 tumour necrosis factor receptor, and ankylosing spondylitis in UK Caucasians

Abstract:

Objectives: To replicate the possible genetic association between ankylosing spondylitis (AS) and TNFRSF1A.

Methods: TNFRSF1A was re-sequenced in 48 individuals with AS to identify novel polymorphisms. Nine single nucleotide polymorphisms (SNPs) in TNFRSF1A and 5 SNPs in the neighbouring gene SCNN1A were genotyped in 1604 UK Caucasian individuals with AS and 1019 matched controls. An extended study was implemented using additional genotype data on 8 of ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Big Data Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Expand authors...

Contributors

Publisher:
Clinical and Experimental Rheumatology Publisher's website
Journal:
Clinical and Experimental Rheumatology Journal website
Volume:
30
Issue:
1
Pages:
110-113
Publication date:
2012-03-07
Acceptance date:
2011-09-20
EISSN:
1593-098X
ISSN:
0392-856X
Source identifiers:
245858
Language:
English
Keywords:
Pubs id:
pubs:245858
UUID:
uuid:a34cfda4-5a14-46e5-b327-c7ee32592947
Local pid:
pubs:245858
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP