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Journal article

Evidence of genetic association between TNFRSF1A encoding the p55 tumour necrosis factor receptor, and ankylosing spondylitis in UK Caucasians.

Abstract:

OBJECTIVES: To replicate the possible genetic association between ankylosing spondylitis (AS) and TNFRSF1A. METHODS: TNFRSF1A was re-sequenced in 48 individuals with AS to identify novel polymorphisms. Nine single nucleotide polymorphisms (SNPs) in TNFRSF1A and 5 SNPs in the neighbouring gene SCNN1A were genotyped in 1604 UK Caucasian individuals with AS and 1019 matched controls. An extended study was implemented using additional genotype data on 8 of these SNPs from 1400 historical controls...

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Publication status:
Published

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Journal:
Clinical and experimental rheumatology
Volume:
30
Issue:
1
Pages:
110-113
Publication date:
2012-01-01
EISSN:
1593-098X
ISSN:
0392-856X
URN:
uuid:a34cfda4-5a14-46e5-b327-c7ee32592947
Source identifiers:
245858
Local pid:
pubs:245858

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