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Trigeminal nociceptive transmission in migraineurs predicts migraine attacks.

Abstract:

Several lines of evidence suggest a major role of the trigeminovascular system in the pathogenesis of migraine. Using functional magnetic resonance imaging (fMRI), we compared brain responses during trigeminal pain processing in migraine patients with those of healthy control subjects. The main finding is that the activity of the spinal trigeminal nuclei in response to nociceptive stimulation showed a cycling behavior over the migraine interval. Although interictal (i.e., outside of attack) m...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
31
Issue:
6
Pages:
1937-1943
Publication date:
2011-02-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:a336d4b7-82be-4f2c-a5f2-fe3de469c556
Source identifiers:
241881
Local pid:
pubs:241881

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