Journal article icon

Journal article

In vivo evaluation and dosimetry of 123I-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT, in an R1M rhabdomyosarcoma athymic mouse model.

Abstract:

UNLABELLED: Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, it was shown that in tumor cells in vitro the L-amino acid transporter system seemed to lack stereospecificity. Because of the successful results with 123/125I-2-iodo-L-phenylalanine, 123/125I-2-iodo-D-phenylalanine was developed, and its tumor-detecting characteristics were evaluated in vivo. METHODS: 123I labeling of 2-iodo-D-phenylalanine was performed with a kit formulation by ...

Expand abstract
Publication status:
Published

Actions


Authors


Kersemans, V More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Kersemans, K More by this author
Thierens, H More by this author
Expand authors...
Journal:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Volume:
46
Issue:
12
Pages:
2104-2111
Publication date:
2005-12-05
EISSN:
1535-5667
ISSN:
0161-5505
URN:
uuid:a31290ce-f7ee-4f45-9013-9ffb388ae77b
Source identifiers:
258001
Local pid:
pubs:258001

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP