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Canomad presenting without ophthalmoplegia and responding to intravenous immunoglobulin.

Abstract:

The acronym CANOMAD encompasses chronic ataxic neuropathy combined with ophthalmoplegia, M protein, cold agglutinins, and anti-disialosyl antibodies.Herein we describe 2 patients presenting with progressive ataxic neuropathy who only developed ophthalmoplegia after a significant delay post-presentation, which in 1 case had features indicative of brainstem dysfunction. Both patients were found to have an IgM paraprotein and anti-disialosyl antibodies. They responded to treatment with intraveno...

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Publisher copy:
10.1002/mus.22167

Authors


Balaratnam, MS More by this author
Riordan-Eva, P More by this author
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Journal:
Muscle and nerve
Volume:
44
Issue:
5
Pages:
829-833
Publication date:
2011-11-05
DOI:
EISSN:
1097-4598
ISSN:
0148-639X
URN:
uuid:a2da2bab-9aae-4fab-afe7-c1f0ca8b1629
Source identifiers:
365759
Local pid:
pubs:365759

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