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Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

Abstract:

BACKGROUND: Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal adenocarcinoma. However, only a few patients with Barrett's oesophagus develop adenocarcinoma, which complicates clinical management in the absence of valid predictors. Within an international consortium investigating the genetics of Barrett's oesophagus and oesophageal adenocarcinoma, we aimed to identify novel genetic...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/S1470-2045(16)30240-6

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Department:
Oxford, MSD, NDM, Human Genetics Wt Centre
Role:
Author
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US National Cancer Institute More from this funder
US National Institutes of Health More from this funder
National Health and Medical Research Council of Australia More from this funder
Swedish Cancer Society More from this funder
Medical Research Council More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
Lancet Oncol Journal website
Publication date:
2016-08-12
Acceptance date:
2016-06-07
DOI:
ISSN:
1474-5488
Pubs id:
pubs:639118
URN:
uri:a2a1925a-8748-40ba-80d6-3da2dfee7983
UUID:
a2a1925a-8748-40ba-80d6-3da2dfee7983
Local pid:
pubs:639118
Language:
English
Keywords:

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