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Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC)

Abstract:

A western lifestyle, characterised by low rates of energy expenditure and a high-energy diet rich in animal protein, saturated fats and refined carbohydrates, is associated with high incidence of prostate cancer in men. A high-energy nutritional status results in insulin/IGF signalling in cells, which in turn stimulates synthesis of fatty acids. We investigated whether the genetic variability of the genes belonging to the fatty acid synthesis pathway is related to prostate cancer risk in 815 ...

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Publisher copy:
10.1016/j.ejca.2010.09.029

Authors


Hüsing, A More by this author
Chang-Claude, J More by this author
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Journal:
European Journal of Cancer
Volume:
47
Issue:
3
Pages:
420-427
Publication date:
2011-02-05
DOI:
ISSN:
0959-8049
URN:
uuid:a252b53d-b770-4993-b098-bff36683800b
Source identifiers:
118160
Local pid:
pubs:118160

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