Mosquito transmission, growth phenotypes and the virulence of malaria parasites.

Journal article

BACKGROUND: A series of elegant experiments was recently published which demonstrated that transmission of malaria parasites through mosquitoes elicited an attenuated growth phenotype, whereby infections grew more slowly and reached peak parasitaemia at least five-fold lower than parasites which had not been mosquito transmitted. To assess the implications of these results it is essential to understand whether the attenuated infection phenotype is a general phenomenon across parasites genotyp...

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Authors: Pollitt, L; Mackinnon, M; Mideo, N; Read, A

• Publication status: Published
• Journal: Malaria journal
• Volume: 12
• Issue: 1
• Pages: 440
• Publication date: 2013-01-01
• DOI: 10.1186/1475-2875-12-440
• EISSN: 1475-2875
• ISSN: 1475-2875
• Language: English
• Keywords: Research Design; Virulence; Phenotype; Culicidae; Biomedical Research; Malaria; Plasmodium chabaudi; Mice; Animals