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Mosquito transmission, growth phenotypes and the virulence of malaria parasites.

Abstract:

BACKGROUND: A series of elegant experiments was recently published which demonstrated that transmission of malaria parasites through mosquitoes elicited an attenuated growth phenotype, whereby infections grew more slowly and reached peak parasitaemia at least five-fold lower than parasites which had not been mosquito transmitted. To assess the implications of these results it is essential to understand whether the attenuated infection phenotype is a general phenomenon across parasites genotyp...

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Publication status:
Published

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Publisher copy:
10.1186/1475-2875-12-440

Authors


Pollitt, LC More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Journal:
Malaria journal
Volume:
12
Issue:
1
Pages:
440
Publication date:
2013
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:a2510190-9b86-4b60-8d86-d6bf8fde6397
Source identifiers:
445072
Local pid:
pubs:445072

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