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Germ layer induction in ESC--following the vertebrate roadmap.

Abstract:

Controlled differentiation of pluripotential cells takes place routinely and with great success in developing vertebrate embryos. It therefore makes sense to take note of how this is achieved and use this knowledge to control the differentiation of embryonic stem cells (ESCs). An added advantage is that the differentiated cells resulting from this process in embryos have proven functionality and longevity. This unit reviews what is known about the embryonic signals that drive differentiation ...

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, BHF Centre of Research Excellence
Role:
Author
Journal:
Current protocols in stem cell biology
Volume:
Chapter 1
Pages:
Unit-1D.1
Publication date:
2007-06-05
DOI:
EISSN:
1938-8969
ISSN:
1941-7322
URN:
uuid:a22d8cd8-9f30-45e0-8b15-0251d9a45836
Source identifiers:
106309
Local pid:
pubs:106309

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