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An electrochemical adaptation of Ellman's test.

Abstract:

The electrochemically initiated reaction of thiols with N,N-diethyl-p-phenylenediamine has been coupled with an existing colorimetric sensing reaction developed by Ellman as a means of providing an electrochemical adaptation of the latter whereby the total thiol species present in a sample can be determined. The detection methodology has been proven to be robust with a linear range for cysteine from 2-120 microM, a limit of detection of 1.17 microM and has shown selectivity against a wide ran...

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Publication status:
Published

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Publisher copy:
10.1039/b202780c

Authors


Nekrassova, O More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Hignett, G More by this author
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Journal:
The Analyst
Volume:
127
Issue:
6
Pages:
797-802
Publication date:
2002-06-05
DOI:
EISSN:
1364-5528
ISSN:
0003-2654
URN:
uuid:a21913ee-9c1c-4729-9fb3-1abab15082d2
Source identifiers:
32164
Local pid:
pubs:32164
Language:
English

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