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Acute anxiolytic effects of cocaine: the role of test latency and activity phase.

Abstract:

The emotional effects of the initial consumption of cocaine can have a strong influence on the subsequent use of this drug. Several studies in rodents using long test latencies have reported anxiogenic effects of cocaine. Anxiogenesis, however, would seem to contradict cocaine's well known rewarding effects and its abuse liability. The present study was set up to shed light on conditions that influence cocaine's consequences, namely the time after administration and active vs. resting test ph...

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Publisher copy:
10.1016/j.pbb.2007.12.013

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Pharmacology, biochemistry, and behavior
Volume:
89
Issue:
2
Pages:
218-226
Publication date:
2008-04-05
DOI:
EISSN:
1873-5177
ISSN:
0091-3057
URN:
uuid:a1f6b8b0-ab92-48b5-a2c6-1669f483af1e
Source identifiers:
242114
Local pid:
pubs:242114

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