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Journal article

Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.

Abstract:

The ADAMTS proteinases are a family of secreted, matrix-associated enzymes that have diverse roles in the regulation of tissue organization and vascular homeostasis. Several of the 19 human family members have been identified as having either tumor promoting or suppressing roles. We previously demonstrated that decreased ADAMTS15 expression correlated with a worse clinical outcome in mammary carcinoma (e.g., Porter et al., Int J Cancer 2006;118:1241-7). We have explored the effects of A Disin...

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Publication status:
Published

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Publisher copy:
10.1002/ijc.29129

Authors


Kelwick, R More by this author
Wagstaff, L More by this author
Cooley, LS More by this author
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Journal:
International journal of cancer. Journal international du cancer
Volume:
136
Issue:
4
Pages:
E14-E26
Publication date:
2015-02-05
DOI:
EISSN:
1097-0215
ISSN:
0020-7136
URN:
uuid:a1ecfc35-be87-4e0b-a227-8c73b4f4b298
Source identifiers:
479671
Local pid:
pubs:479671

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