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The genetics of circadian rhythms, sleep and health

Abstract:

Circadian rhythms are 24-h rhythms in physiology and behaviour generated by molecular clocks, which serve to coordinate internal time with the external world. The circadian system is a master regulator of nearly all physiology and its disruption has major consequences on health. Sleep and circadian rhythm disruption (SCRD) is a ubiquitous feature in today’s 24/7 society, and studies on shift-workers have shown that SCRD can lead not only to cognitive impairment, but also metabolic syndrome an...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/hmg/ddx240

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
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Funding agency for:
Jagannath, A
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Funding agency for:
Wakaf, Z
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Funding agency for:
Vasudevan, SR
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Publisher:
Oxford University Press Publisher's website
Journal:
Human Molecular Genetics Journal website
Volume:
26
Issue:
R2
Pages:
R128–R138
Publication date:
2017-07-14
Acceptance date:
2017-06-21
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
Pubs id:
pubs:732815
URN:
uri:a1d86a17-aced-49d9-8ead-eff8cd40960e
UUID:
uuid:a1d86a17-aced-49d9-8ead-eff8cd40960e
Local pid:
pubs:732815
Language:
English

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