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Journal article

Comparison of cluster-based and source-attribution methods for estimating transmission risk using large HIV sequence databases

Abstract:

Phylogenetic clustering of HIV sequences from a random sample of patients can reveal epidemiological transmission patterns, but interpretation is hampered by limited theoretical support and statistical properties of clustering analysis remain poorly understood. Alternatively, source attribution methods allow fitting of HIV transmission models and thereby quantify aspects of disease transmission. A simulation study was conducted to assess error rates of clustering methods for detecting transmi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.epidem.2017.10.001

Authors


Ratmann, O More by this author
Delpech, V More by this author
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Publisher:
Elsevier Publisher's website
Journal:
Epidemics Journal website
Volume:
23
Pages:
1-10
Publication date:
2017-10-20
Acceptance date:
2017-10-17
DOI:
EISSN:
1878-0067
ISSN:
1755-4365
Pubs id:
pubs:743434
URN:
uri:a1d86206-dcbb-4075-b05b-9f509c9c56ef
UUID:
uuid:a1d86206-dcbb-4075-b05b-9f509c9c56ef
Local pid:
pubs:743434

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