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Altered cortical beta-band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis

Abstract:

Continuous rhythmic neuronal oscillations underpin local and regional cortical communication. The impact of the motor system neurodegenerative syndrome amyotrophic lateral sclerosis (ALS) on the neuronal oscillations subserving movement might therefore serve as a sensitive marker of disease activity. Movement preparation and execution are consistently associated with modulations to neuronal oscillation beta (15-30 Hz) power. Cortical beta-band oscillations were measured using magnetoencephalo...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/hbm.23357

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Department:
Oxford, MSD, Oxford Centre for Human Brain Activity
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Department:
Oxford, MSD, Oxford Centre for Human Brain Activity
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Department:
Oxford, MSD, Oxford Centre for Human Brain Activity
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Department:
Oxford, MSD, Oxford Centre for Human Brain Activity
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Funding agency for:
Proudfoot, M
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Funding agency for:
Colclough, GL
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Funding agency for:
Woolrich, M
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Funding agency for:
Nobre, AC
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Publisher:
Wiley Publisher's website
Journal:
Human Brain Mapping Journal website
Publication date:
2016-09-13
Acceptance date:
2016-08-12
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
Pubs id:
pubs:638402
URN:
uri:a1a6f9e0-2a13-4421-ab73-276dfe14a117
UUID:
a1a6f9e0-2a13-4421-ab73-276dfe14a117
Local pid:
pubs:638402

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