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Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy

Abstract:

Non-freezing cold injury (NFCI) develops after sustained exposure to cold temperatures, resulting in tissue cooling but not freezing. This can result in persistent sensory disturbance of the hands and feet including numbness, paraesthesia and chronic pain. Both vascular and neurological aetiologies of this pain have been suggested but remain unproven. We prospectively approached patients referred for clinical assessment of chronic pain following non-freezing cold injury between 12 February 20...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/brain/awx215

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Department:
Oxford, MSD, Clinical Neurosciences
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Department:
Oxford, MSD, Clinical Neurosciences
Polydefkis, M More by this author
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Funding agency for:
Vale, TA
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Funding agency for:
Bennett, DLH
Ministry of Defence More from this funder
Wellcome Trust More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Brain Journal website
Volume:
140
Issue:
10
Pages:
2557–2569
Publication date:
2017-08-31
Acceptance date:
2017-07-06
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Pubs id:
pubs:714155
URN:
uri:a19dfcc7-69f7-44d5-88a0-c586a43c0319
UUID:
uuid:a19dfcc7-69f7-44d5-88a0-c586a43c0319
Local pid:
pubs:714155
Paper number:
10

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