Journal article icon

Journal article

Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. II. Studies of B73.1 antibody-antigen interaction on the lymphocyte membrane.

Abstract:

In this paper, we characterize the antigen recognized by the monoclonal antibody B73.1 and the modification occurring at the membrane of the positive cells after interaction with the antibody. The B73.1-defined antigen is a protein of 50,000 to 72,000 daltons that is sensitive to pronase but not to trypsin treatment. B73.1 antibody, and its F(ab')2 fragment, directly block, at high concentrations, the binding of IgG antibody-sensitized erythrocytes to the Fc receptors (FcR) of a subpopulation...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Expand authors...
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
130
Issue:
5
Pages:
2142-2148
Publication date:
1983-05-05
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:a178ce74-1ed0-4517-ba91-ca3a38ebccb3
Source identifiers:
19986
Local pid:
pubs:19986

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP