Journal article icon

Journal article

Techniques for analysing pattern formation in populations of stem cells and their progeny.

Abstract:

BACKGROUND: To investigate how patterns of cell differentiation are related to underlying intra- and inter-cellular signalling pathways, we use a stochastic individual-based model to simulate pattern formation when stem cells and their progeny are cultured as a monolayer. We assume that the fate of an individual cell is regulated by the signals it receives from neighbouring cells via either diffusive or juxtacrine signalling. We analyse simulated patterns using two different spatial statisti...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1186/1471-2105-12-396

Authors


Fozard, JA More by this author
Kirkham, GR More by this author
Buttery, LD More by this author
Jensen, OE More by this author
Expand authors...
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
BMC bioinformatics Journal website
Volume:
12
Issue:
1
Pages:
396
Publication date:
2011
DOI:
EISSN:
1471-2105
ISSN:
1471-2105
URN:
uuid:a176bf8b-b6d9-4a0d-82a7-f3259031038b
Source identifiers:
319114
Local pid:
pubs:319114

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP