Journal article
Identification of immunodominant responses to the Plasmodium falciparum antigens PfUIS3, PfLSA1 and PfLSAP2 in multiple strains of mice
- Abstract:
-
Malaria, caused by the Plasmodium parasite, remains a serious global public health concern. A vaccine could have a substantial impact on eliminating this disease, alongside other preventative measures. We recently described the development of three novel, viral vectored vaccines expressing either of the antigens PfUIS3, PfLSA1 and PfLSAP2. Each vaccination regimen provided high levels of protection against chimeric parasite challenge in a mouse model, largely dependent on CD8+ T cells. In thi...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 973.6KB, Terms of use)
-
- Publisher copy:
- 10.1371/journal.pone.0144515
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLOS One More from this journal
- Volume:
- 10
- Issue:
- 12
- Article number:
- e0144515
- Publication date:
- 2015-12-01
- DOI:
- EISSN:
-
1932-6203
Item Description
- Keywords:
- Pubs id:
-
pubs:585821
- UUID:
-
uuid:a15b5b3a-ed3b-4e3a-9597-e5ad2ab245e1
- Local pid:
-
pubs:585821
- Source identifiers:
-
585821
- Deposit date:
-
2016-01-14
Terms of use
- Copyright holder:
- Longley et al
- Copyright date:
- 2015
- Notes:
- Copyright: © 2015 Longley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record