Thesis
Cancer metabolic pathways regulated by hypoxia
- Abstract:
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Metabolic reprogramming in cancer cells provides energy and important metabolites required to sustain tumour proliferation. Hypoxia represents a hostile environment that can encourage these transformations and other adaptive responses that contribute to poor prognosis and resistance to radiation and chemotherapy. Hypoxic signatures associated with worse prognosis were previously derived in different cancer types, and led to the selection of two candidates with potential metabolic implicati...
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Bibliographic Details
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:a148c7a8-cb0c-4760-8073-678299fd837d
- Local pid:
- ora:7263
- Deposit date:
- 2013-09-09
Terms of use
- Copyright holder:
- Favaro, E
- Copyright date:
- 2013
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