Journal article icon

Journal article

Genome-wide association study identifies five loci associated with lung function.

Abstract:

Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV(1)) and the ratio of FEV(1) to forced vital capacity (FVC) in the SpiroMeta consortium (n = 20,288 individuals of European ancestry). We conducted a meta-analysis of top signals with data from direct genotyping (n < or = 32,184 additional individuals) and in silico summary a...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/ng.501

Authors


Journal:
Nature genetics More from this journal
Volume:
42
Issue:
1
Pages:
36-44
Publication date:
2010-01-01
DOI:
EISSN:
1546-1718
ISSN:
1061-4036

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP