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Regulatory T cells and transplantation tolerance.

Abstract:

Rodent models of transplantation have demonstrated that it is possible to induce specific immunological tolerance of donor antigens and indefinite graft survival in the absence of any continued immunosuppression. If this situation could be achieved clinically it would avoid many of the longer term complications of organ grafting, such as the increased risk of infection and cancer and the nephrotoxicity of many immunosuppressive agents. In this review we shall consider the interplay between re...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of nephrology
Volume:
21
Issue:
4
Pages:
485-496
Publication date:
2008-01-01
EISSN:
1724-6059
ISSN:
1121-8428
Source identifiers:
2711
Language:
English
Keywords:
Pubs id:
pubs:2711
UUID:
uuid:a13b858a-85da-4822-b8de-0207ccb1191d
Local pid:
pubs:2711
Deposit date:
2012-12-19

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