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Preparation of recombinant fibronectin fragments for functional and structural studies.

Abstract:

Fibronectin, an ubiquitous extracellular matrix (ECM) glycoprotein, plays a major role in fundamental biological processes such as cell adhesion and migration, maintenance of normal cell morphology, cytoskeletal organization, and cell differentiation. Fibronectin is constructed from three types of independently folding protein module (Fn1, Fn2, and Fn3) and is found as a Fibrillar network in the ECM where it interacts with other ECM components and provides anchorage sites for cell surface int...

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Publisher copy:
10.1007/978-1-59745-413-1_5

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
522
Pages:
73-99
Publication date:
2009-01-01
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Language:
English
Keywords:
Pubs id:
pubs:7482
UUID:
uuid:a1371b4e-74ee-4864-906d-432b1ec921b0
Local pid:
pubs:7482
Source identifiers:
7482
Deposit date:
2012-12-19

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