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Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza

Abstract:

Background Patients with asthma are at risk of hospitalisation with influenza, but the reasons for this predisposition are unknown.

Study setting A prospective observational study of adults with PCR-confirmed influenza in 11 UK hospitals, measuring nasal, nasopharyngeal and systemic immune mediators and whole-blood gene expression.

Results Of 133 admissions, 40 (30%) had previous asthma; these were more often female (70% ve...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Role:
Author
ORCID:
0000-0002-8413-7738
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-4035-4562
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Role:
Author
ORCID:
0000-0002-3220-8346
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Role:
Author
ORCID:
0000-0003-3052-2793
Publisher:
European Respiratory Society
Journal:
European Respiratory Journal More from this journal
Volume:
54
Issue:
4
Article number:
1900949
Place of publication:
England
Publication date:
2019-08-07
Acceptance date:
2019-07-25
DOI:
EISSN:
1399-3003
ISSN:
0903-1936
Pmid:
31391224
Language:
English
Keywords:
Pubs id:
1072716
Local pid:
pubs:1072716
Deposit date:
2021-05-19

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