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Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians

Abstract:

The naturally mummified remains of a mother and two daughters found in an 18th century Hungarian crypt were analysed, using multiple molecular genetic techniques to examine the epidemiology and evolution of tuberculosis. DNA was amplified from a number of targets on the Mycobacterium tuberculosis genome, including DNA from IS6110, gyrA, katG codon 463, oxyR, dnaA-dnaN, mtp40, plcD and the direct repeat (DR) region. The strains present in the mummified remains were identified as M. tuberculosi...

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Publisher copy:
10.1099/mic.0.25961-0

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Microbiology
Volume:
149
Issue:
1
Pages:
143-151
Publication date:
2003-01-01
DOI:
ISSN:
1350-0872
Language:
English
Pubs id:
pubs:315247
UUID:
uuid:a11b5c08-1ce2-4218-9148-40cd0fd4b27c
Local pid:
pubs:315247
Source identifiers:
315247
Deposit date:
2012-12-19

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