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Journal article

Cluster crossover trial of head positioning in acute stroke

Abstract:

Background

Outcomes in patients with acute ischemic stroke could be improved by lying flat, i.e., fully supine with the back horizontal and the face upwards, to increase cerebral perfusion. Evidence to guide head positioning after stroke is limited and the lying flat position may increase the risk of pneumonia.

Methods

In a pragmatic, cluster randomized crossover trial conducted in nine countries, we randomly assigned 11,094 patients with acute stroke, 85% of whic...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1056/NEJMoa1615715

Authors


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Publisher:
Massachusetts Medical Society Publisher's website
Journal:
New England Journal of Medicine Journal website
Volume:
376
Pages:
2437-2447
Publication date:
2017-06-01
Acceptance date:
2017-03-21
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Source identifiers:
687222
Keywords:
Pubs id:
pubs:687222
UUID:
uuid:a11b1fca-4db5-442f-bf50-c5f699c19808
Local pid:
pubs:687222
Deposit date:
2017-03-27

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