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Similar selective factors affect both between-gene and between-exon divergence in Drosophila.

Abstract:

As a consequence of alternative splicing, a gene's exons will have different frequencies of inclusion into mature mRNA and different patterns of expression. These differences affect their patterns of evolutionary divergence. Using the recently reannotated genome of Drosophila melanogaster and the genome sequences of four closely related species of the melanogaster subgroup, we investigated the effect of alternative splicing, inclusion level (defined as the number of transcripts an exon is fou...

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Publisher copy:
10.1093/molbev/msp006

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Molecular biology and evolution More from this journal
Volume:
26
Issue:
4
Pages:
859-866
Publication date:
2009-04-01
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
Language:
English
Keywords:
Pubs id:
pubs:237652
UUID:
uuid:a1089a4d-a2a3-4bd3-9b29-ac70ff4f01ee
Local pid:
pubs:237652
Source identifiers:
237652
Deposit date:
2012-12-19

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