Brainstem motor loops in the control of movement.

Journal article

In recent years, the role of the area around the upper brainstem, particularly the pedunculopontine (PPN) region and the zona incerta (ZI), in the initiation and control of movement has generated much clinical interest. Using electrophysiological and pharmacological methods, we have further explored these structures and their influence in motor control in the nonhuman primate and in patients with proximal tremor. We have found that lesioning the PPN and electrical stimulation at high frequenc...

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Authors: Nandi, D; Aziz, T; Liu, X; Stein, J

• Publication status: Published
• Journal: Movement disorders : official journal of the Movement Disorder Society
• Volume: 17 Suppl 3
• Issue: SUPPL. 3
• Pages: S22-S27
• Publication date: 2002-01-01
• DOI: 10.1002/mds.10139
• EISSN: 1531-8257
• ISSN: 0885-3185
• Language: English
• Keywords: Movement; Brain Stem; Muscimol; Neural Pathways; MPTP Poisoning; Bicuculline; Humans; Macaca mulatta; GABA Agonists; GABA Antagonists; Motor Activity; Subthalamus; Electric Stimulation; Animals; Tegmentum Mesencephali; Tremor